Albumin Globulin Ratio Calculator

The Albumin Globulin (A/G) Ratio Calculator helps healthcare professionals and patients understand the relationship between two important proteins in the blood: albumin and globulin. This ratio is a valuable diagnostic tool for assessing liver function, nutritional status, and various medical conditions.

What is the Albumin Globulin Ratio?

The A/G ratio measures the balance between two major protein groups in your blood:

Albumin

Most abundant protein in blood
Produced by the liver
Helps maintain blood pressure
Transports various substances through blood
Normal range: 3.5-5.2 g/dL

Globulin

Produced by liver and immune system
Includes important antibodies
Helps fight infections
Normal range: 2.6-3.5 g/dL

Clinical Significance

The A/G ratio is used to:

Screen for liver disease
Assess nutritional status
Evaluate kidney function
Monitor immune system disorders
Detect certain cancers

Normal Values

The normal A/G ratio typically falls within these ranges:

Most common range: 1.2-2.2
Extended range: 1.1-2.5
Values <1.0 or >2.5 may indicate underlying conditions

Understanding Results

High A/G Ratio (>2.5)

May indicate:

Dehydration
Leukemia
Immunodeficiency disorders
Certain medications

Low A/G Ratio (<1.0)

May indicate:

Liver disease
Kidney disease
Autoimmune conditions
Multiple myeloma
Chronic inflammation

Calculation Method

The A/G ratio is calculated using this formula:

A/G Ratio = Albumin / (Total Protein - Albumin)

Where:

Albumin and Total Protein are measured in g/dL
Globulin is calculated by subtracting Albumin from Total Protein

Important Notes

Results should always be interpreted by a healthcare professional
The A/G ratio should be considered alongside other clinical findings
Multiple factors can affect protein levels in blood
Follow-up testing may be needed to confirm diagnoses

This calculator is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment.